Massive-sdAB-FAST anti-CTLA4

This kit provides ready-to-use binders for DNA-PAINT imaging of CTLA-4, also known as CD152 or Cytotoxic T-Lymphocyte Associated Antigen 4, an immune checkpoint receptor that regulates T cell activation. CTLA-4 inhibits immune responses by binding to co-stimulatory molecules. Also included are imager strands and buffers for sample preparation and imaging.

This kit contains single-domain antibody (sdAB) binders that recognize CTLA4 and are coupled to FAST DNA-PAINT sequence F2. Each sdAB is coupled to a single DNA-PAINT docking strand.

sdABs developed and manufactured by NanoTag Biotechnologies are sold under license. Unmodified and fluorophore- coupled sdABs (FluoTag®) remain available for direct purchase from NanoTag Biotechnologies.

Protocol/Datasheet for MASSIVE-sdAB-FAST anti-CTLA4